Overview of the epidemiology and the threat of Klebsiella pneumoniae carbapenemases (KPC) resistance

Klebsiella pneumoniae carbapenemases (KPCs) confer resistance to nearly all β-lactams. This broad-spectrum drug resistance mechanism has rapidly spread in the United States and is reportedly increasing elsewhere in the world. Thus, the emergence of KPC resistance is a major threat to global health....

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Detalles Bibliográficos
Autores principales: Chen, Luke F, Anderson, Deverick J, Paterson, David L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460674/
https://www.ncbi.nlm.nih.gov/pubmed/23055754
http://dx.doi.org/10.2147/IDR.S26613
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author Chen, Luke F
Anderson, Deverick J
Paterson, David L
author_facet Chen, Luke F
Anderson, Deverick J
Paterson, David L
author_sort Chen, Luke F
collection PubMed
description Klebsiella pneumoniae carbapenemases (KPCs) confer resistance to nearly all β-lactams. This broad-spectrum drug resistance mechanism has rapidly spread in the United States and is reportedly increasing elsewhere in the world. Thus, the emergence of KPC resistance is a major threat to global health. This article reviews the epidemiology and provides an overview of the dissemination of KPC-producing organisms.
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spelling pubmed-34606742012-10-09 Overview of the epidemiology and the threat of Klebsiella pneumoniae carbapenemases (KPC) resistance Chen, Luke F Anderson, Deverick J Paterson, David L Infect Drug Resist Review Klebsiella pneumoniae carbapenemases (KPCs) confer resistance to nearly all β-lactams. This broad-spectrum drug resistance mechanism has rapidly spread in the United States and is reportedly increasing elsewhere in the world. Thus, the emergence of KPC resistance is a major threat to global health. This article reviews the epidemiology and provides an overview of the dissemination of KPC-producing organisms. Dove Medical Press 2012-09-24 /pmc/articles/PMC3460674/ /pubmed/23055754 http://dx.doi.org/10.2147/IDR.S26613 Text en © 2012 Chen et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Review
Chen, Luke F
Anderson, Deverick J
Paterson, David L
Overview of the epidemiology and the threat of Klebsiella pneumoniae carbapenemases (KPC) resistance
title Overview of the epidemiology and the threat of Klebsiella pneumoniae carbapenemases (KPC) resistance
title_full Overview of the epidemiology and the threat of Klebsiella pneumoniae carbapenemases (KPC) resistance
title_fullStr Overview of the epidemiology and the threat of Klebsiella pneumoniae carbapenemases (KPC) resistance
title_full_unstemmed Overview of the epidemiology and the threat of Klebsiella pneumoniae carbapenemases (KPC) resistance
title_short Overview of the epidemiology and the threat of Klebsiella pneumoniae carbapenemases (KPC) resistance
title_sort overview of the epidemiology and the threat of klebsiella pneumoniae carbapenemases (kpc) resistance
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460674/
https://www.ncbi.nlm.nih.gov/pubmed/23055754
http://dx.doi.org/10.2147/IDR.S26613
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