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Multifocal photodynamic therapy for diffuse choroidal hemangioma

BACKGROUND: A choroidal hemangioma is an uncommon benign vascular tumor of the choroid that can be either circumscribed or diffuse. In our experience, diffuse choroidal hemangiomas in Asian patients often require multiple photodynamic therapy (PDT) treatment sessions. METHODS: We here provide a case...

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Autores principales: Ang, Marcus, Lee, Shu-Yen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460716/
https://www.ncbi.nlm.nih.gov/pubmed/23055665
http://dx.doi.org/10.2147/OPTH.S35471
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author Ang, Marcus
Lee, Shu-Yen
author_facet Ang, Marcus
Lee, Shu-Yen
author_sort Ang, Marcus
collection PubMed
description BACKGROUND: A choroidal hemangioma is an uncommon benign vascular tumor of the choroid that can be either circumscribed or diffuse. In our experience, diffuse choroidal hemangiomas in Asian patients often require multiple photodynamic therapy (PDT) treatment sessions. METHODS: We here provide a case report of a 7-year-old boy with Sturge–Weber syndrome who presented with diffuse choroidal hemangioma in the left eye. Five sessions of PDT treatment were required over a period of 1 year and a final optical coherence tomogram 3 months later revealed resolution of subretinal fluid and the choroidal hemangioma. RESULTS: Final visual acuity was 20/100 in the left eye with resolution of subretinal fluid. This case report illustrates that a single application of PDT using standard published parameters was insufficient to achieve the destruction of the enlarged vessels. This experience is similar to previous Chinese reports on circumscribed choroidal hemangiomas. The decision for repeat treatment was based on subretinal fluid recurrence, rather than complete tumor regression. CONCLUSION: Our case report supports previous suggestions that larger dilated vessels in the vascular network of a choroidal hemangioma might affect the efficacy and selectivity of PDT in treating the eyes of Asian patients – which may explain the need for multiple treatments.
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spelling pubmed-34607162012-10-09 Multifocal photodynamic therapy for diffuse choroidal hemangioma Ang, Marcus Lee, Shu-Yen Clin Ophthalmol Case Report BACKGROUND: A choroidal hemangioma is an uncommon benign vascular tumor of the choroid that can be either circumscribed or diffuse. In our experience, diffuse choroidal hemangiomas in Asian patients often require multiple photodynamic therapy (PDT) treatment sessions. METHODS: We here provide a case report of a 7-year-old boy with Sturge–Weber syndrome who presented with diffuse choroidal hemangioma in the left eye. Five sessions of PDT treatment were required over a period of 1 year and a final optical coherence tomogram 3 months later revealed resolution of subretinal fluid and the choroidal hemangioma. RESULTS: Final visual acuity was 20/100 in the left eye with resolution of subretinal fluid. This case report illustrates that a single application of PDT using standard published parameters was insufficient to achieve the destruction of the enlarged vessels. This experience is similar to previous Chinese reports on circumscribed choroidal hemangiomas. The decision for repeat treatment was based on subretinal fluid recurrence, rather than complete tumor regression. CONCLUSION: Our case report supports previous suggestions that larger dilated vessels in the vascular network of a choroidal hemangioma might affect the efficacy and selectivity of PDT in treating the eyes of Asian patients – which may explain the need for multiple treatments. Dove Medical Press 2012 2012-09-07 /pmc/articles/PMC3460716/ /pubmed/23055665 http://dx.doi.org/10.2147/OPTH.S35471 Text en © 2012 Ang and Lee, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Case Report
Ang, Marcus
Lee, Shu-Yen
Multifocal photodynamic therapy for diffuse choroidal hemangioma
title Multifocal photodynamic therapy for diffuse choroidal hemangioma
title_full Multifocal photodynamic therapy for diffuse choroidal hemangioma
title_fullStr Multifocal photodynamic therapy for diffuse choroidal hemangioma
title_full_unstemmed Multifocal photodynamic therapy for diffuse choroidal hemangioma
title_short Multifocal photodynamic therapy for diffuse choroidal hemangioma
title_sort multifocal photodynamic therapy for diffuse choroidal hemangioma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460716/
https://www.ncbi.nlm.nih.gov/pubmed/23055665
http://dx.doi.org/10.2147/OPTH.S35471
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