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Genome-wide recruitment to Polycomb-modified chromatin and activity regulation of the synovial sarcoma oncogene SYT-SSX2

BACKGROUND: SYT-SSX is the oncogene associated with synovial sarcoma (SS), a stem cell disease. SYT-SSX is thought to be responsible for sarcoma initiation and development. It interacts with components of Polycomb and SWI/SNF complexes, the two epigenetic controllers that maintain the heritable stat...

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Detalles Bibliográficos
Autores principales:	Garcia, Christina B, Shaffer, Christian M, Eid, Josiane E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460777/ https://www.ncbi.nlm.nih.gov/pubmed/22594313 http://dx.doi.org/10.1186/1471-2164-13-189

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