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Subdominant Antigens in Bacterial Vaccines: AM779 Is Subdominant in the Anaplasma marginale Outer Membrane Vaccine but Does Not Associate with Protective Immunity
Identification of specific antigens responsible for the ability of complex immunogens to induce protection is a major goal in development of bacterial vaccines. Much of the investigation has focused on highly abundant and highly immunodominant outer membrane proteins. Recently however, genomic and p...
Autores principales: | Albarrak, Saleh M., Brown, Wendy C., Noh, Susan M., Reif, Kathryn E., Scoles, Glen A., Turse, Joshua E., Norimine, Junzo, Ueti, Massaro W., Palmer, Guy H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460813/ https://www.ncbi.nlm.nih.gov/pubmed/23029498 http://dx.doi.org/10.1371/journal.pone.0046372 |
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