The Homozygote VCP(R155H/R155H) Mouse Model Exhibits Accelerated Human VCP-Associated Disease Pathology

Valosin containing protein (VCP) mutations are the cause of hereditary inclusion body myopathy, Paget's disease of bone, frontotemporal dementia (IBMPFD). VCP gene mutations have also been linked to 2% of isolated familial amyotrophic lateral sclerosis (ALS). VCP is at the intersection of disru...

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Detalles Bibliográficos
Autores principales: Nalbandian, Angèle, Llewellyn, Katrina J., Kitazawa, Masashi, Yin, Hong Z., Badadani, Mallikarjun, Khanlou, Negar, Edwards, Robert, Nguyen, Christopher, Mukherjee, Jogeshwar, Mozaffar, Tahseen, Watts, Giles, Weiss, John, Kimonis, Virginia E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460820/
https://www.ncbi.nlm.nih.gov/pubmed/23029473
http://dx.doi.org/10.1371/journal.pone.0046308

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