Pericentrin in health and disease: Exploring the patchwork of Pericentrin splice variants

Researchers around the world perform large-scale screens to identify disease-related gene defects in humans. One of the genes of interest is Pericentrin (PCNT), a gene which codes for a large coiled-coil protein with multiple functions in the cell. Recently, we showed that different Pericentrin (Pcn...

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Detalles Bibliográficos
Autores principales: Mühlhans, Johanna, Gießl, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460829/
https://www.ncbi.nlm.nih.gov/pubmed/23060948
http://dx.doi.org/10.4161/cib.20363
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author Mühlhans, Johanna
Gießl, Andreas
author_facet Mühlhans, Johanna
Gießl, Andreas
author_sort Mühlhans, Johanna
collection PubMed
description Researchers around the world perform large-scale screens to identify disease-related gene defects in humans. One of the genes of interest is Pericentrin (PCNT), a gene which codes for a large coiled-coil protein with multiple functions in the cell. Recently, we showed that different Pericentrin (Pcnt) splice variants are differentially distributed among sensory tissues of the mouse, emphasizing the importance of a protein‘s spliceome for the function of a cell.
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spelling pubmed-34608292012-10-11 Pericentrin in health and disease: Exploring the patchwork of Pericentrin splice variants Mühlhans, Johanna Gießl, Andreas Commun Integr Biol Short Communication Researchers around the world perform large-scale screens to identify disease-related gene defects in humans. One of the genes of interest is Pericentrin (PCNT), a gene which codes for a large coiled-coil protein with multiple functions in the cell. Recently, we showed that different Pericentrin (Pcnt) splice variants are differentially distributed among sensory tissues of the mouse, emphasizing the importance of a protein‘s spliceome for the function of a cell. Landes Bioscience 2012-07-01 /pmc/articles/PMC3460829/ /pubmed/23060948 http://dx.doi.org/10.4161/cib.20363 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Short Communication
Mühlhans, Johanna
Gießl, Andreas
Pericentrin in health and disease: Exploring the patchwork of Pericentrin splice variants
title Pericentrin in health and disease: Exploring the patchwork of Pericentrin splice variants
title_full Pericentrin in health and disease: Exploring the patchwork of Pericentrin splice variants
title_fullStr Pericentrin in health and disease: Exploring the patchwork of Pericentrin splice variants
title_full_unstemmed Pericentrin in health and disease: Exploring the patchwork of Pericentrin splice variants
title_short Pericentrin in health and disease: Exploring the patchwork of Pericentrin splice variants
title_sort pericentrin in health and disease: exploring the patchwork of pericentrin splice variants
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460829/
https://www.ncbi.nlm.nih.gov/pubmed/23060948
http://dx.doi.org/10.4161/cib.20363
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