Cdc42 regulation of polarized traffic in fission yeast

Cdc42 is a key factor in the control of cell polarity and morphogenesis. Fission yeast Cdc42 regulates formin activation and actin cable assembly. Cdc42 is also required for exocyst function, contributing to polarized secretion. Additionally, Cdc42 participates in membrane trafficking, endosome recy...

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Detalles Bibliográficos
Autores principales: Estravis, Miguel, Rincon, Sergio, Pérez, Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Article Addendum
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460842/
https://www.ncbi.nlm.nih.gov/pubmed/23060961
http://dx.doi.org/10.4161/cib.19977
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author Estravis, Miguel
Rincon, Sergio
Pérez, Pilar
author_facet Estravis, Miguel
Rincon, Sergio
Pérez, Pilar
author_sort Estravis, Miguel
collection PubMed
description Cdc42 is a key factor in the control of cell polarity and morphogenesis. Fission yeast Cdc42 regulates formin activation and actin cable assembly. Cdc42 is also required for exocyst function, contributing to polarized secretion. Additionally, Cdc42 participates in membrane trafficking, endosome recycling, and vacuole formation. We show here how Cdc42 is required for the correct transport/recycling to the plasma membrane of the glucan synthases Bgs1 and Bgs4, responsible of cell wall biosynthesis and polarized growth at the cell tips.
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spelling pubmed-34608422012-10-11 Cdc42 regulation of polarized traffic in fission yeast Estravis, Miguel Rincon, Sergio Pérez, Pilar Commun Integr Biol Article Addendum Cdc42 is a key factor in the control of cell polarity and morphogenesis. Fission yeast Cdc42 regulates formin activation and actin cable assembly. Cdc42 is also required for exocyst function, contributing to polarized secretion. Additionally, Cdc42 participates in membrane trafficking, endosome recycling, and vacuole formation. We show here how Cdc42 is required for the correct transport/recycling to the plasma membrane of the glucan synthases Bgs1 and Bgs4, responsible of cell wall biosynthesis and polarized growth at the cell tips. Landes Bioscience 2012-07-01 /pmc/articles/PMC3460842/ /pubmed/23060961 http://dx.doi.org/10.4161/cib.19977 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Article Addendum
Estravis, Miguel
Rincon, Sergio
Pérez, Pilar
Cdc42 regulation of polarized traffic in fission yeast
title Cdc42 regulation of polarized traffic in fission yeast
title_full Cdc42 regulation of polarized traffic in fission yeast
title_fullStr Cdc42 regulation of polarized traffic in fission yeast
title_full_unstemmed Cdc42 regulation of polarized traffic in fission yeast
title_short Cdc42 regulation of polarized traffic in fission yeast
title_sort cdc42 regulation of polarized traffic in fission yeast
topic Article Addendum
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460842/
https://www.ncbi.nlm.nih.gov/pubmed/23060961
http://dx.doi.org/10.4161/cib.19977
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