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Endothelin-1 Augments Na(+)/H(+) Exchange Activity in Murine Pulmonary Arterial Smooth Muscle Cells via Rho Kinase

Excessive production of endothelin-1 (ET-1), a potent vasoconstrictor, occurs with several forms of pulmonary hypertension. In addition to modulating vasomotor tone, ET-1 can potentiate pulmonary arterial smooth muscle cell (PASMC) growth and migration, both of which contribute to the vascular remod...

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Detalles Bibliográficos
Autores principales:	Undem, Clark, Rios, Eon J., Maylor, Julie, Shimoda, Larissa A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460862/ https://www.ncbi.nlm.nih.gov/pubmed/23029469 http://dx.doi.org/10.1371/journal.pone.0046303

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