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Molecular Characterisation of Endogenous Vangl2/Vangl1 Heteromeric Protein Complexes

BACKGROUND: Mutations in the Planar Cell Polarity (PCP) core gene Vangl2 cause the most severe neural tube defects (NTD) in mice and humans. Genetic studies show that the Vangl2 gene genetically interacts with a close homologue Vangl1. How precisely Vangl2 and Vangl1 proteins interact and crosstalk...

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Detalles Bibliográficos
Autores principales:	Belotti, Edwige, Puvirajesinghe, Tania M., Audebert, Stéphane, Baudelet, Emilie, Camoin, Luc, Pierres, Michel, Lasvaux, Lea, Ferracci, Géraldine, Montcouquiol, Mireille, Borg, Jean-Paul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460870/ https://www.ncbi.nlm.nih.gov/pubmed/23029439 http://dx.doi.org/10.1371/journal.pone.0046213

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