Cargando…

The Transcriptional Targets of Mutant FOXL2 in Granulosa Cell Tumours

BACKGROUND: Despite their distinct biology, granulosa cell tumours (GCTs) are treated the same as other ovarian tumours. Intriguingly, a recurring somatic mutation in the transcription factor Forkhead Box L2 (FOXL2) 402C>G has been found in nearly all GCTs examined. This investigation aims to ide...

Descripción completa

Detalles Bibliográficos
Autores principales: Rosario, Roseanne, Araki, Hiromitsu, Print, Cristin G., Shelling, Andrew N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460904/
https://www.ncbi.nlm.nih.gov/pubmed/23029457
http://dx.doi.org/10.1371/journal.pone.0046270