The Polyoma Virus Large T Binding Protein p150 Is a Transcriptional Repressor of c-MYC

p150, product of the SALL2 gene, is a binding partner of the polyoma virus large T antigen and a putative tumor suppressor. p150 binds to the nuclease hypersensitive element of the c-MYC promoter and represses c-MYC transcription. Overexpression of p150 in human ovarian surface epithelial cells lead...

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Detalles Bibliográficos
Autores principales: Sung, Chang Kyoo, Yim, Hyungshin, Gu, Hongcang, Li, Dawei, Andrews, Erik, Duraisamy, Sekhar, Li, Cheng, Drapkin, Ronny, Benjamin, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460914/
https://www.ncbi.nlm.nih.gov/pubmed/23029531
http://dx.doi.org/10.1371/journal.pone.0046486

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