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Identification, Characterization and Application of a G-Quadruplex Structured DNA Aptamer against Cancer Biomarker Protein Anterior Gradient Homolog 2
BACKGROUND: Anterior gradient homolog 2 (AGR2) is a functional protein with critical roles in a diverse range of biological systems, including vertebrate tissue development, inflammatory tissue injury responses, and cancer progression. Clinical studies have shown that the AGR2 protein is overexpress...
Autores principales: | Wu, Jie, Wang, Chi, Li, Xilan, Song, Yanling, Wang, Wei, Li, Cong, Hu, Jia, Zhu, Zhi, Li, Jiuxing, Zhang, Weiyun, Lu, Zhongxian, Yang, Chaoyong James |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460915/ https://www.ncbi.nlm.nih.gov/pubmed/23029506 http://dx.doi.org/10.1371/journal.pone.0046393 |
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