Cargando…
LXR-Mediated Inhibition of CD4(+) T Helper Cells
T(H)17 cells, which require the expression of both retinoic acid receptor-related orphan receptors α and γt (RORαand RORγt) for full differentiation and function, have been implicated as major effectors in the pathogenesis of inflammatory and autoimmune diseases. We recently demonstrated that the Li...
Autores principales: | Solt, Laura A., Kamenecka, Theodore M., Burris, Thomas P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460920/ https://www.ncbi.nlm.nih.gov/pubmed/23029557 http://dx.doi.org/10.1371/journal.pone.0046615 |
Ejemplares similares
-
Correction: Pharmacological and Genetic Modulation of REV-ERB Activity and Expression Affects Orexigenic Gene Expression
por: Amador, Ariadna, et al.
Publicado: (2016) -
Pharmacological Targeting the REV-ERBs in Sleep/Wake Regulation
por: Amador, Ariadna, et al.
Publicado: (2016) -
Development of LXR inverse agonists to treat MAFLD, NASH, and other metabolic diseases
por: Griffett, Kristine, et al.
Publicado: (2023) -
The nuclear receptor REV-ERBα modulates Th17 cell-mediated autoimmune disease
por: Chang, Christina, et al.
Publicado: (2019) -
Phytosterols Inhibit Side-Chain Oxysterol Mediated Activation of LXR in Breast Cancer Cells
por: Hutchinson, Samantha A., et al.
Publicado: (2019)