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Amplified and Homozygously Deleted Genes in Glioblastoma: Impact on Gene Expression Levels
BACKGROUND: Glioblastoma multiforme (GBM) displays multiple amplicons and homozygous deletions that involve relevant pathogenic genes and other genes whose role remains unknown. METHODOLOGY: Single-nucleotide polymorphism (SNP)-arrays were used to determine the frequency of recurrent amplicons and h...
Autores principales: | Crespo, Inês, Tão, Hermínio, Nieto, Ana Belen, Rebelo, Olinda, Domingues, Patrícia, Vital, Ana Luísa, Patino, Maria del Carmen, Barbosa, Marcos, Lopes, Maria Celeste, Oliveira, Catarina Resende, Orfao, Alberto, Tabernero, María Dolores |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460955/ https://www.ncbi.nlm.nih.gov/pubmed/23029397 http://dx.doi.org/10.1371/journal.pone.0046088 |
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