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Amplified and Homozygously Deleted Genes in Glioblastoma: Impact on Gene Expression Levels

BACKGROUND: Glioblastoma multiforme (GBM) displays multiple amplicons and homozygous deletions that involve relevant pathogenic genes and other genes whose role remains unknown. METHODOLOGY: Single-nucleotide polymorphism (SNP)-arrays were used to determine the frequency of recurrent amplicons and h...

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Detalles Bibliográficos
Autores principales: Crespo, Inês, Tão, Hermínio, Nieto, Ana Belen, Rebelo, Olinda, Domingues, Patrícia, Vital, Ana Luísa, Patino, Maria del Carmen, Barbosa, Marcos, Lopes, Maria Celeste, Oliveira, Catarina Resende, Orfao, Alberto, Tabernero, María Dolores
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460955/
https://www.ncbi.nlm.nih.gov/pubmed/23029397
http://dx.doi.org/10.1371/journal.pone.0046088

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