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(-)-Epigallocatechin-3-Gallate Protects against NO-Induced Ototoxicity through the Regulation of Caspase- 1, Caspase-3, and NF-κB Activation

Excessive nitric oxide (NO) production is toxic to the cochlea and induces hearing loss. However, the mechanism through which NO induces ototoxicity has not been completely understood. The aim of this study was to gain further insight into the mechanism mediating NO-induced toxicity in auditory HEI-...

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Detalles Bibliográficos
Autores principales: Kim, Su-Jin, Lee, Jeong-Han, Kim, Beom-Su, So, Hong-Seob, Park, Raekil, Myung, Noh-Yil, Um, Jae-Young, Hong, Seung-Heon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461011/
https://www.ncbi.nlm.nih.gov/pubmed/23028481
http://dx.doi.org/10.1371/journal.pone.0043967