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Multiscale Modeling of Metabolism and Macromolecular Synthesis in E. coli and Its Application to the Evolution of Codon Usage

Biological systems are inherently hierarchal and multiscale in time and space. A major challenge of systems biology is to describe biological systems as a computational model, which can be used to derive novel hypothesis and drive experiments leading to new knowledge. The constraint-based reconstruc...

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Detalles Bibliográficos
Autores principales:	Thiele, Ines, Fleming, Ronan M. T., Que, Richard, Bordbar, Aarash, Diep, Dinh, Palsson, Bernhard O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461016/ https://www.ncbi.nlm.nih.gov/pubmed/23029152 http://dx.doi.org/10.1371/journal.pone.0045635

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