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Validation of Drug-Like Inhibitors against Mycobacterium Tuberculosis L-Aspartate α-Decarboxylase Using Nuclear Magnetic Resonance ((1)H NMR)

The catalytic activity of L-aspartate α-decarboxylase (ADC) is essential for the growth of several micro-organisms, including Mycobacterium tuberculosis (Mtb), and has triggered efforts for the development of pharmaceutically active compounds against tuberculosis. The present study is a continuation...

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Detalles Bibliográficos
Autores principales: Sharma, Reetu, Florea, Mara, Nau, Werner M., Swaminathan, Kunchithapadam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461031/
https://www.ncbi.nlm.nih.gov/pubmed/23029336
http://dx.doi.org/10.1371/journal.pone.0045947