Implication of DNA Demethylation and Bivalent Histone Modification for Selective Gene Regulation in Mouse Primordial Germ Cells

Primordial germ cells (PGCs) sequentially induce specific genes required for their development. We focused on epigenetic changes that regulate PGC-specific gene expression. mil-1, Blimp1, and Stella are preferentially expressed in PGCs, and their expression is upregulated during PGC differentiation....

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Detalles Bibliográficos
Autores principales: Mochizuki, Kentaro, Tachibana, Makoto, Saitou, Mitinori, Tokitake, Yuko, Matsui, Yasuhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461056/
https://www.ncbi.nlm.nih.gov/pubmed/23029374
http://dx.doi.org/10.1371/journal.pone.0046036

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