Ixabepilone-associated peripheral neuropathy: data from across the phase II and III clinical trials

PURPOSE: Dose-limiting neuropathy is a major adverse event associated with most of the microtubule-stabilizing agent-based chemotherapy regimens. Ixabepilone, a semisynthetic analogue of the natural epothilone B, has activity against a wide range of tumor types. Peripheral neuropathy (PN), associate...

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Detalles Bibliográficos
Autores principales: Vahdat, Linda T., Thomas, Eva S., Roché, Henri H., Hortobagyi, Gabriel N., Sparano, Joseph A., Yelle, Louise, Fornier, Monica N., Martín, Miguel, Bunnell, Craig A., Mukhopadhyay, Pralay, Peck, Ronald A., Perez, Edith A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461204/
https://www.ncbi.nlm.nih.gov/pubmed/22382588
http://dx.doi.org/10.1007/s00520-012-1384-0

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