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Immunity to Sand Fly Salivary Protein LJM11 Modulates Host Response to Vector-Transmitted Leishmania Conferring Ulcer-Free Protection
Leishmania vaccines that protect against needle challenge fail against the potency of a Leishmania-infected sand fly transmission. Here, we demonstrate that intradermal immunization of mice with 500 ng of the sand fly salivary recombinant protein LJM11 (rLJM11) from Lutzomyia longipalpis, in the abs...
Autores principales: | Gomes, Regis, Oliveira, Fabiano, Teixeira, Clarissa, Meneses, Claudio, Gilmore, Dana C, Elnaiem, Dia-Eldin, Kamhawi, Shaden, Valenzuela, Jesus G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461249/ https://www.ncbi.nlm.nih.gov/pubmed/22739793 http://dx.doi.org/10.1038/jid.2012.205 |
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