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Nrf2/ARE Signaling Pathway: Key Mediator in Oxidative Stress and Potential Therapeutic Target in ALS

Nrf2 (nuclear erythroid 2-related factor 2) is a basic region leucine-zipper transcription factor which binds to the antioxidant response element (ARE) and thereby regulates the expression of a large battery of genes involved in the cellular antioxidant and anti-inflammatory defence as well as mitoc...

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Detalles Bibliográficos
Autores principales: Petri, Susanne, Körner, Sonja, Kiaei, Mahmoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461296/
https://www.ncbi.nlm.nih.gov/pubmed/23050144
http://dx.doi.org/10.1155/2012/878030