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Knock-down of Kaiso induces proliferation and blocks granulocytic differentiation in blast crisis of chronic myeloid leukemia

BACKGROUND: Kaiso protein has been identified as a new member of the POZ-ZF subfamily of transcription factors that are involved in development and cancer. There is consistent evidence of the role of Kaiso and its involvement in human tumorigenesis but there is no evidence about its role in hematopo...

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Detalles Bibliográficos
Autores principales: Cofre, Jaime, Menezes, João R L, Pizzatti, Luciana, Abdelhay, Eliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461418/
https://www.ncbi.nlm.nih.gov/pubmed/22709531
http://dx.doi.org/10.1186/1475-2867-12-28