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Seasonal performance of a malaria rapid diagnosis test at community health clinics in a malaria-hyperendemic region of Burkina Faso
BACKGOUND: Treatment of confirmed malaria patients with Artemisinin-based Combination Therapy (ACT) at remote areas is the goal of many anti-malaria programs. Introduction of effective and affordable malaria Rapid Diagnosis Test (RDT) in remote areas could be an alternative tool for malaria case man...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461428/ https://www.ncbi.nlm.nih.gov/pubmed/22647557 http://dx.doi.org/10.1186/1756-3305-5-103 |
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author | Diarra, Amidou Nébié, Issa Tiono, Alfred Sanon, Souleymane Soulama, Issiaka Ouédraogo, Alphonse Gansané, Adama Yaro, Jean B Ouédraogo, Espérance Traoré, Alfred S Sirima, Sodiomon B |
author_facet | Diarra, Amidou Nébié, Issa Tiono, Alfred Sanon, Souleymane Soulama, Issiaka Ouédraogo, Alphonse Gansané, Adama Yaro, Jean B Ouédraogo, Espérance Traoré, Alfred S Sirima, Sodiomon B |
author_sort | Diarra, Amidou |
collection | PubMed |
description | BACKGOUND: Treatment of confirmed malaria patients with Artemisinin-based Combination Therapy (ACT) at remote areas is the goal of many anti-malaria programs. Introduction of effective and affordable malaria Rapid Diagnosis Test (RDT) in remote areas could be an alternative tool for malaria case management. This study aimed to assess performance of the OptiMAL dipstick for rapid malaria diagnosis in children under five. METHODS: Malaria symptomatic and asymptomatic children were recruited in a passive manner in two community clinics (CCs). Malaria diagnosis by microscopy and RDT were performed. Performance of the tests was determined. RESULTS: RDT showed similar ability (61.2%) to accurately diagnose malaria as microscopy (61.1%). OptiMAL showed a high level of sensitivity and specificity, compared with microscopy, during both transmission seasons (high & low), with a sensitivity of 92.9% vs. 74.9% and a specificity of 77.2% vs. 87.5%. CONCLUSION: By improving the performance of the test through accurate and continuous quality control of the device in the field, OptiMAL could be suitable for use at CCs for the management and control of malaria. |
format | Online Article Text |
id | pubmed-3461428 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-34614282012-10-02 Seasonal performance of a malaria rapid diagnosis test at community health clinics in a malaria-hyperendemic region of Burkina Faso Diarra, Amidou Nébié, Issa Tiono, Alfred Sanon, Souleymane Soulama, Issiaka Ouédraogo, Alphonse Gansané, Adama Yaro, Jean B Ouédraogo, Espérance Traoré, Alfred S Sirima, Sodiomon B Parasit Vectors Research BACKGOUND: Treatment of confirmed malaria patients with Artemisinin-based Combination Therapy (ACT) at remote areas is the goal of many anti-malaria programs. Introduction of effective and affordable malaria Rapid Diagnosis Test (RDT) in remote areas could be an alternative tool for malaria case management. This study aimed to assess performance of the OptiMAL dipstick for rapid malaria diagnosis in children under five. METHODS: Malaria symptomatic and asymptomatic children were recruited in a passive manner in two community clinics (CCs). Malaria diagnosis by microscopy and RDT were performed. Performance of the tests was determined. RESULTS: RDT showed similar ability (61.2%) to accurately diagnose malaria as microscopy (61.1%). OptiMAL showed a high level of sensitivity and specificity, compared with microscopy, during both transmission seasons (high & low), with a sensitivity of 92.9% vs. 74.9% and a specificity of 77.2% vs. 87.5%. CONCLUSION: By improving the performance of the test through accurate and continuous quality control of the device in the field, OptiMAL could be suitable for use at CCs for the management and control of malaria. BioMed Central 2012-05-30 /pmc/articles/PMC3461428/ /pubmed/22647557 http://dx.doi.org/10.1186/1756-3305-5-103 Text en Copyright ©2012 Diarra et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Diarra, Amidou Nébié, Issa Tiono, Alfred Sanon, Souleymane Soulama, Issiaka Ouédraogo, Alphonse Gansané, Adama Yaro, Jean B Ouédraogo, Espérance Traoré, Alfred S Sirima, Sodiomon B Seasonal performance of a malaria rapid diagnosis test at community health clinics in a malaria-hyperendemic region of Burkina Faso |
title | Seasonal performance of a malaria rapid diagnosis test at community health clinics in a malaria-hyperendemic region of Burkina Faso |
title_full | Seasonal performance of a malaria rapid diagnosis test at community health clinics in a malaria-hyperendemic region of Burkina Faso |
title_fullStr | Seasonal performance of a malaria rapid diagnosis test at community health clinics in a malaria-hyperendemic region of Burkina Faso |
title_full_unstemmed | Seasonal performance of a malaria rapid diagnosis test at community health clinics in a malaria-hyperendemic region of Burkina Faso |
title_short | Seasonal performance of a malaria rapid diagnosis test at community health clinics in a malaria-hyperendemic region of Burkina Faso |
title_sort | seasonal performance of a malaria rapid diagnosis test at community health clinics in a malaria-hyperendemic region of burkina faso |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461428/ https://www.ncbi.nlm.nih.gov/pubmed/22647557 http://dx.doi.org/10.1186/1756-3305-5-103 |
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