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5-Fluorouracil induces apoptosis in rat cardiocytes through intracellular oxidative stress
BACKGROUND: Cardiotoxicity is a major complication of anticancer drugs, including anthracyclines and 5-fluorouracil(5-FU) and it can have detrimental effects both in patients and workers involved in the preparation of chemotherapy. METHODS: Specifically, we have assessed the effects of increasing co...
Autores principales: | Lamberti, Monica, Porto, Stefania, Marra, Monica, Zappavigna, Silvia, Grimaldi, Anna, Feola, Daniela, Pesce, Delia, Naviglio, Silvio, Spina, Annamaria, Sannolo, Nicola, Caraglia, Michele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461434/ https://www.ncbi.nlm.nih.gov/pubmed/22812382 http://dx.doi.org/10.1186/1756-9966-31-60 |
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