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The protective effect of peroxiredoxin II on oxidative stress induced apoptosis in pancreatic β-cells
Excessive loss of pancreatic β-cells, mainly through apoptosis, contributes to the development of diabetic hyperglycemia. Oxidative stress plays a major role in the process of β-cell apoptosis due to low expression level of endogenous antioxidants in the β-cells. Peroxiredoxins (PRDX) are a family o...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461449/ https://www.ncbi.nlm.nih.gov/pubmed/22709359 http://dx.doi.org/10.1186/2045-3701-2-22 |