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The protective effect of peroxiredoxin II on oxidative stress induced apoptosis in pancreatic β-cells

Excessive loss of pancreatic β-cells, mainly through apoptosis, contributes to the development of diabetic hyperglycemia. Oxidative stress plays a major role in the process of β-cell apoptosis due to low expression level of endogenous antioxidants in the β-cells. Peroxiredoxins (PRDX) are a family o...

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Detalles Bibliográficos
Autores principales: Zhao, Fang, Wang, Qinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461449/
https://www.ncbi.nlm.nih.gov/pubmed/22709359
http://dx.doi.org/10.1186/2045-3701-2-22