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Group I PAKs function downstream of Rac to promote podosome invasion during myoblast fusion in vivo
The p21-activated kinases (PAKs) play essential roles in diverse cellular processes and are required for cell proliferation, apoptosis, polarity establishment, migration, and cell shape changes. Here, we have identified a novel function for the group I PAKs in cell–cell fusion. We show that the two...
Autores principales: | Duan, Rui, Jin, Peng, Luo, Fengbao, Zhang, Guofeng, Anderson, Nathan, Chen, Elizabeth H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461515/ https://www.ncbi.nlm.nih.gov/pubmed/23007650 http://dx.doi.org/10.1083/jcb.201204065 |
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