Cargando…
Cluster Headache Secondary to Macroprolactinoma with Ipsilateral Cavernous Sinus Invasion
We present a 25 year-old man with episodic cluster headache that was refractory to all standard pharmacological prophylactic and abortive treatments. Because of the lack of response, an MRI brain was performed which showed a large pituitary tumour with ipsilateral cavernous sinus invasion. The serum...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461630/ https://www.ncbi.nlm.nih.gov/pubmed/23050176 http://dx.doi.org/10.1155/2012/830469 |
_version_ | 1782245104528916480 |
---|---|
author | Levy, M. J. Robertson, I. Howlett, T. A. |
author_facet | Levy, M. J. Robertson, I. Howlett, T. A. |
author_sort | Levy, M. J. |
collection | PubMed |
description | We present a 25 year-old man with episodic cluster headache that was refractory to all standard pharmacological prophylactic and abortive treatments. Because of the lack of response, an MRI brain was performed which showed a large pituitary tumour with ipsilateral cavernous sinus invasion. The serum prolactin was significantly elevated at 54,700 miU/L (50–400) confirming a macro-prolactinoma. Within a few days of cabergoline therapy the headache resolved. He continues to be headache free several years after starting the dopamine agonist. This case highlights the importance of imaging the pituitary fossa in patients with refractory cluster headache, It also raises the potential anatomical importance of the cavernous sinus in pituitary-associated headache. |
format | Online Article Text |
id | pubmed-3461630 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-34616302012-10-04 Cluster Headache Secondary to Macroprolactinoma with Ipsilateral Cavernous Sinus Invasion Levy, M. J. Robertson, I. Howlett, T. A. Case Rep Neurol Med Case Report We present a 25 year-old man with episodic cluster headache that was refractory to all standard pharmacological prophylactic and abortive treatments. Because of the lack of response, an MRI brain was performed which showed a large pituitary tumour with ipsilateral cavernous sinus invasion. The serum prolactin was significantly elevated at 54,700 miU/L (50–400) confirming a macro-prolactinoma. Within a few days of cabergoline therapy the headache resolved. He continues to be headache free several years after starting the dopamine agonist. This case highlights the importance of imaging the pituitary fossa in patients with refractory cluster headache, It also raises the potential anatomical importance of the cavernous sinus in pituitary-associated headache. Hindawi Publishing Corporation 2012 2012-09-23 /pmc/articles/PMC3461630/ /pubmed/23050176 http://dx.doi.org/10.1155/2012/830469 Text en Copyright © 2012 M. J. Levy et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Levy, M. J. Robertson, I. Howlett, T. A. Cluster Headache Secondary to Macroprolactinoma with Ipsilateral Cavernous Sinus Invasion |
title | Cluster Headache Secondary to Macroprolactinoma with Ipsilateral Cavernous Sinus Invasion |
title_full | Cluster Headache Secondary to Macroprolactinoma with Ipsilateral Cavernous Sinus Invasion |
title_fullStr | Cluster Headache Secondary to Macroprolactinoma with Ipsilateral Cavernous Sinus Invasion |
title_full_unstemmed | Cluster Headache Secondary to Macroprolactinoma with Ipsilateral Cavernous Sinus Invasion |
title_short | Cluster Headache Secondary to Macroprolactinoma with Ipsilateral Cavernous Sinus Invasion |
title_sort | cluster headache secondary to macroprolactinoma with ipsilateral cavernous sinus invasion |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461630/ https://www.ncbi.nlm.nih.gov/pubmed/23050176 http://dx.doi.org/10.1155/2012/830469 |
work_keys_str_mv | AT levymj clusterheadachesecondarytomacroprolactinomawithipsilateralcavernoussinusinvasion AT robertsoni clusterheadachesecondarytomacroprolactinomawithipsilateralcavernoussinusinvasion AT howlettta clusterheadachesecondarytomacroprolactinomawithipsilateralcavernoussinusinvasion |