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Select Small Core Structure Carbamates Exhibit High Contact Toxicity to “Carbamate-Resistant” Strain Malaria Mosquitoes, Anopheles gambiae (Akron)
Acetylcholinesterase (AChE) is a proven target for control of the malaria mosquito (Anopheles gambiae). Unfortunately, a single amino acid mutation (G119S) in An. gambiae AChE-1 (AgAChE) confers resistance to the AChE inhibitors currently approved by the World Health Organization for indoor residual...
Autores principales: | Wong, Dawn M., Li, Jianyong, Chen, Qiao-Hong, Han, Qian, Mutunga, James M., Wysinski, Ania, Anderson, Troy D., Ding, Haizhen, Carpenetti, Tiffany L., Verma, Astha, Islam, Rafique, Paulson, Sally L., Lam, Polo C.-H., Totrov, Maxim, Bloomquist, Jeffrey R., Carlier, Paul R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462181/ https://www.ncbi.nlm.nih.gov/pubmed/23049714 http://dx.doi.org/10.1371/journal.pone.0046712 |
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