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3D Domain Swapping Causes Extensive Multimerisation of Human Interleukin-10 When Expressed In Planta

Heterologous expression platforms of biopharmaceutical proteins have been significantly improved over the last decade. Further improvement can be established by examining the intrinsic properties of proteins. Interleukin-10 (IL-10) is an anti-inflammatory cytokine with a short half-life that plays a...

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Detalles Bibliográficos
Autores principales:	Westerhof, Lotte B., Wilbers, Ruud H. P., Roosien, Jan, van de Velde, Jan, Goverse, Aska, Bakker, Jaap, Schots, Arjen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462211/ https://www.ncbi.nlm.nih.gov/pubmed/23049703 http://dx.doi.org/10.1371/journal.pone.0046460

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