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The Interplay of Public Intervention and Private Choices in Determining the Outcome of Vaccination Programmes

After a long period of stagnation, traditionally explained by the voluntary nature of the programme, a considerable increase in routine measles vaccine uptake has been recently observed in Italy after a set of public interventions aiming to promote MMR immunization, whilst retaining its voluntary as...

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Detalles Bibliográficos
Autores principales: d’Onofrio, Alberto, Manfredi, Piero, Poletti, Piero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462214/
https://www.ncbi.nlm.nih.gov/pubmed/23049682
http://dx.doi.org/10.1371/journal.pone.0045653
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author d’Onofrio, Alberto
Manfredi, Piero
Poletti, Piero
author_facet d’Onofrio, Alberto
Manfredi, Piero
Poletti, Piero
author_sort d’Onofrio, Alberto
collection PubMed
description After a long period of stagnation, traditionally explained by the voluntary nature of the programme, a considerable increase in routine measles vaccine uptake has been recently observed in Italy after a set of public interventions aiming to promote MMR immunization, whilst retaining its voluntary aspect. To account for this take-off in coverage we propose a simple SIR transmission model with vaccination choice, where, unlike similar works, vaccinating behaviour spreads not only through the diffusion of “private” information spontaneously circulating among parents of children to be vaccinated, which we call imitation, but also through public information communicated by the public health authorities. We show that public intervention has a stabilising role which is able to reduce the strength of imitation-induced oscillations, to allow disease elimination, and to even make the disease-free equilibrium where everyone is vaccinated globally attractive. The available Italian data are used to evaluate the main behavioural parameters, showing that the proposed model seems to provide a much more plausible behavioural explanation of the observed take-off of uptake of vaccine against measles than models based on pure imitation alone.
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spelling pubmed-34622142012-10-05 The Interplay of Public Intervention and Private Choices in Determining the Outcome of Vaccination Programmes d’Onofrio, Alberto Manfredi, Piero Poletti, Piero PLoS One Research Article After a long period of stagnation, traditionally explained by the voluntary nature of the programme, a considerable increase in routine measles vaccine uptake has been recently observed in Italy after a set of public interventions aiming to promote MMR immunization, whilst retaining its voluntary aspect. To account for this take-off in coverage we propose a simple SIR transmission model with vaccination choice, where, unlike similar works, vaccinating behaviour spreads not only through the diffusion of “private” information spontaneously circulating among parents of children to be vaccinated, which we call imitation, but also through public information communicated by the public health authorities. We show that public intervention has a stabilising role which is able to reduce the strength of imitation-induced oscillations, to allow disease elimination, and to even make the disease-free equilibrium where everyone is vaccinated globally attractive. The available Italian data are used to evaluate the main behavioural parameters, showing that the proposed model seems to provide a much more plausible behavioural explanation of the observed take-off of uptake of vaccine against measles than models based on pure imitation alone. Public Library of Science 2012-10-01 /pmc/articles/PMC3462214/ /pubmed/23049682 http://dx.doi.org/10.1371/journal.pone.0045653 Text en © 2012 d’Onofrio et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
d’Onofrio, Alberto
Manfredi, Piero
Poletti, Piero
The Interplay of Public Intervention and Private Choices in Determining the Outcome of Vaccination Programmes
title The Interplay of Public Intervention and Private Choices in Determining the Outcome of Vaccination Programmes
title_full The Interplay of Public Intervention and Private Choices in Determining the Outcome of Vaccination Programmes
title_fullStr The Interplay of Public Intervention and Private Choices in Determining the Outcome of Vaccination Programmes
title_full_unstemmed The Interplay of Public Intervention and Private Choices in Determining the Outcome of Vaccination Programmes
title_short The Interplay of Public Intervention and Private Choices in Determining the Outcome of Vaccination Programmes
title_sort interplay of public intervention and private choices in determining the outcome of vaccination programmes
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462214/
https://www.ncbi.nlm.nih.gov/pubmed/23049682
http://dx.doi.org/10.1371/journal.pone.0045653
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