Insulin-like growth factor-II: new roles for an old actor

Insulin-like growth factor-II (IGF-II), traditionally considered as a growth factor implicated in growth of fetal tissues and cancer cells, is now emerging as a potential metabolic regulator. The aim of this overview is to provide the available evidence, obtained in both experimental conditions and...

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Detalles Bibliográficos
Autor principal: Cianfarani, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462314/
https://www.ncbi.nlm.nih.gov/pubmed/23060858
http://dx.doi.org/10.3389/fendo.2012.00118
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author Cianfarani, Stefano
author_facet Cianfarani, Stefano
author_sort Cianfarani, Stefano
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description Insulin-like growth factor-II (IGF-II), traditionally considered as a growth factor implicated in growth of fetal tissues and cancer cells, is now emerging as a potential metabolic regulator. The aim of this overview is to provide the available evidence, obtained in both experimental conditions and in humans, for a role of IGF-II in the fine-tuning of metabolism and body composition. The underlying mechanisms and the potential clinical implications are discussed.
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spelling pubmed-34623142012-10-11 Insulin-like growth factor-II: new roles for an old actor Cianfarani, Stefano Front Endocrinol (Lausanne) Endocrinology Insulin-like growth factor-II (IGF-II), traditionally considered as a growth factor implicated in growth of fetal tissues and cancer cells, is now emerging as a potential metabolic regulator. The aim of this overview is to provide the available evidence, obtained in both experimental conditions and in humans, for a role of IGF-II in the fine-tuning of metabolism and body composition. The underlying mechanisms and the potential clinical implications are discussed. Frontiers Research Foundation 2012-10-02 /pmc/articles/PMC3462314/ /pubmed/23060858 http://dx.doi.org/10.3389/fendo.2012.00118 Text en Copyright © Cianfarani. http://www.frontiersin.org/licenseagreement This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/) , which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc.
spellingShingle Endocrinology
Cianfarani, Stefano
Insulin-like growth factor-II: new roles for an old actor
title Insulin-like growth factor-II: new roles for an old actor
title_full Insulin-like growth factor-II: new roles for an old actor
title_fullStr Insulin-like growth factor-II: new roles for an old actor
title_full_unstemmed Insulin-like growth factor-II: new roles for an old actor
title_short Insulin-like growth factor-II: new roles for an old actor
title_sort insulin-like growth factor-ii: new roles for an old actor
topic Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462314/
https://www.ncbi.nlm.nih.gov/pubmed/23060858
http://dx.doi.org/10.3389/fendo.2012.00118
work_keys_str_mv AT cianfaranistefano insulinlikegrowthfactoriinewrolesforanoldactor

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