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Reprofiling a classical anthelmintic, pyrvinium pamoate, as an anti-cancer drug targeting mitochondrial respiration

Pyrvinium pamoate (PP) is an FDA-approved classical anthelmintic, but is now attracting particular attention as an anti-cancer drug after recent findings of its potent cytotoxicity against various cancer cell lines only during glucose starvation, as well as its anti-tumor activity against hypovascul...

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Detalles Bibliográficos
Autores principales:	Ishii, Isao, Harada, Yasuo, Kasahara, Tadashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2012
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462317/ https://www.ncbi.nlm.nih.gov/pubmed/23061049 http://dx.doi.org/10.3389/fonc.2012.00137

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