Characterization of Zebrafish von Willebrand Factor Reveals Conservation of Domain Structure, Multimerization, and Intracellular Storage

von Willebrand disease (VWD) is the most common inherited human bleeding disorder and is caused by quantitative or qualitative defects in von Willebrand factor (VWF). VWF is a secreted glycoprotein that circulates as large multimers. While reduced VWF is associated with bleeding, elevations in overa...

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Detalles Bibliográficos
Autores principales: Ghosh, Arunima, Vo, Andy, Twiss, Beverly K., Kretz, Colin A., Jozwiak, Mary A., Montgomery, Robert R., Shavit, Jordan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462383/
https://www.ncbi.nlm.nih.gov/pubmed/23049555
http://dx.doi.org/10.1155/2012/214209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462383/
https://www.ncbi.nlm.nih.gov/pubmed/23049555
http://dx.doi.org/10.1155/2012/214209

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