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Phosphatidylinositol 4,5-Biphosphate (PIP(2)) Lipids Regulate the Phosphorylation of Syntaxin N-Terminus by Modulating Both Its Position and Local Structure

[Image: see text] Syntaxin (STX) is a N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) protein that binds to the plasma membrane and regulates ion channels and neurotransmitter transporters. Experiments have established the involvement of the N-terminal segment of STX in direct...

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Detalles Bibliográficos
Autores principales: Khelashvili, George, Galli, Aurelio, Weinstein, Harel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462474/
https://www.ncbi.nlm.nih.gov/pubmed/22950482
http://dx.doi.org/10.1021/bi300833z