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TGF-β sensitivity is determined by N-linked glycosylation of the type II TGF-β receptor

N-linked glycosylation is a critical determinant of protein structure and function, regulating processes such as protein folding, stability and localization, ligand–receptor binding and intracellular signalling. TβRII [type II TGF-β (transforming growth factor β) receptor] plays a crucial role in th...

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Detalles Bibliográficos
Autores principales: Kim, Young-Woong, Park, Jinah, Lee, Hyun-Ju, Lee, So-Young, Kim, Seong-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462611/
https://www.ncbi.nlm.nih.gov/pubmed/22571197
http://dx.doi.org/10.1042/BJ20111923

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