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IL-1 signal affects both protection and pathogenesis of virus-induced chronic CNS demyelinating disease
BACKGROUND: Theiler’s virus infection induces chronic demyelinating disease in mice and has been investigated as an infectious model for multiple sclerosis (MS). IL-1 plays an important role in the pathogenesis of both the autoimmune disease model (EAE) and this viral model for MS. However, IL-1 is...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462702/ https://www.ncbi.nlm.nih.gov/pubmed/22985464 http://dx.doi.org/10.1186/1742-2094-9-217 |