IL-1 signal affects both protection and pathogenesis of virus-induced chronic CNS demyelinating disease

BACKGROUND: Theiler’s virus infection induces chronic demyelinating disease in mice and has been investigated as an infectious model for multiple sclerosis (MS). IL-1 plays an important role in the pathogenesis of both the autoimmune disease model (EAE) and this viral model for MS. However, IL-1 is...

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Detalles Bibliográficos
Autores principales: Kim, Byung S, Jin, Young-Hee, Meng, Liping, Hou, Wanqiu, Kang, Hyun Seok, Park, Hey Suk, Koh, Chang-Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462702/
https://www.ncbi.nlm.nih.gov/pubmed/22985464
http://dx.doi.org/10.1186/1742-2094-9-217

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