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The mitochondrial transporter SLC25A43 is frequently deleted and may influence cell proliferation in HER2-positive breast tumors

BACKGROUND: Overexpression of the human epidermal growth factor receptor (HER) 2 is associated with poor prognosis and shortened survival in breast cancer patients. HER2 is a potent activator of several signaling pathways that support cell survival, proliferation and metabolism. In HER2-positive bre...

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Detalles Bibliográficos
Autores principales: Tina, Elisabet, Lindqvist, Breezy Malakkaran, Gabrielson, Marike, Lubovac, Zelmina, Wegman, Pia, Wingren, Sten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462703/
https://www.ncbi.nlm.nih.gov/pubmed/22883974
http://dx.doi.org/10.1186/1471-2407-12-350

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