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DcR3 binds to ovarian cancer via heparan sulfate proteoglycans and modulates tumor cells response to platinum with corresponding alteration in the expression of BRCA1

BACKGROUND: Overcoming platinum resistance is a major obstacle in the treatment of Epithelial Ovarian Cancer (EOC). In our previous work Decoy Receptor 3 (DcR3) was found to be related to platinum resistance. The major objective of this work was to define the cellular interaction of DcR3 with EOC an...

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Detalles Bibliográficos
Autores principales:	Connor, Joseph P, Felder, Mildred, Kapur, Arvinder, Onujiogu, Nonyem
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462721/ https://www.ncbi.nlm.nih.gov/pubmed/22583667 http://dx.doi.org/10.1186/1471-2407-12-176

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