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Adipose Tissue Promotes a Serum Cytokine Profile Related to Lower Insulin Sensitivity after Chronic Central Leptin Infusion
Obesity is an inflammatory state characterized by an augment in circulating inflammatory factors. Leptin may modulate the synthesis of these factors by white adipose tissue decreasing insulin sensitivity. We have examined the effect of chronic central administration of leptin on circulating levels o...
Autores principales: | Burgos-Ramos, Emma, Canelles, Sandra, Perianes-Cachero, Arancha, Arilla-Ferreiro, Eduardo, Argente, Jesús, Barrios, Vicente |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462753/ https://www.ncbi.nlm.nih.gov/pubmed/23056516 http://dx.doi.org/10.1371/journal.pone.0046893 |
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