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Linkage Disequilibrium Decay and Past Population History in the Human Genome
The fluctuation of population size has not been well studied in the previous studies of theoretical linkage disequilibrium (LD) expectation. In this study, an improved theoretical prediction of LD decay was derived to account for the effects of changes in effective population sizes. The equation was...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Public Library of Science
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462787/ https://www.ncbi.nlm.nih.gov/pubmed/23056365 http://dx.doi.org/10.1371/journal.pone.0046603 |