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Linkage Disequilibrium Decay and Past Population History in the Human Genome

The fluctuation of population size has not been well studied in the previous studies of theoretical linkage disequilibrium (LD) expectation. In this study, an improved theoretical prediction of LD decay was derived to account for the effects of changes in effective population sizes. The equation was...

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Detalles Bibliográficos
Autor principal: Park, Leeyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462787/
https://www.ncbi.nlm.nih.gov/pubmed/23056365
http://dx.doi.org/10.1371/journal.pone.0046603