Ablation of Vacuole Protein Sorting 18 (Vps18) Gene Leads to Neurodegeneration and Impaired Neuronal Migration by Disrupting Multiple Vesicle Transport Pathways to Lysosomes

Intracellular vesicle transport pathways are critical for neuronal survival and central nervous system development. The Vps-C complex regulates multiple vesicle transport pathways to the lysosome in lower organisms. However, little is known regarding its physiological function in mammals. We deleted...

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Detalles Bibliográficos
Autores principales: Peng, Chao, Ye, Jian, Yan, Shunfei, Kong, Shanshan, Shen, Ye, Li, Chenyu, Li, Qinyu, Zheng, Yufang, Deng, Kejing, Xu, Tian, Tao, Wufan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Neurobiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463306/
https://www.ncbi.nlm.nih.gov/pubmed/22854957
http://dx.doi.org/10.1074/jbc.M112.384305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463306/
https://www.ncbi.nlm.nih.gov/pubmed/22854957
http://dx.doi.org/10.1074/jbc.M112.384305

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