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Targeted delivery of tissue plasminogen activator by binding to silica-coated magnetic nanoparticle

BACKGROUND AND METHODS: Silica-coated magnetic nanoparticle (SiO(2)-MNP) prepared by the sol-gel method was studied as a nanocarrier for targeted delivery of tissue plasminogen activator (tPA). The nanocarrier consists of a superparamagnetic iron oxide core and an SiO(2) shell and is characterized b...

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Detalles Bibliográficos
Autores principales:	Chen, Jyh-Ping, Yang, Pei-Ching, Ma, Yunn-Hwa, Tu, Su-Ju, Lu, Yu-Jen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2012
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463402/ https://www.ncbi.nlm.nih.gov/pubmed/23055726 http://dx.doi.org/10.2147/IJN.S36197

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