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XZH-5 Inhibits STAT3 Phosphorylation and Enhances the Cytotoxicity of Chemotherapeutic Drugs in Human Breast and Pancreatic Cancer Cells

Constitutive activation of Signal Transducers and Activators of Transcription 3 (STAT3) signaling is frequently detected in breast and pancreatic cancer. Inhibiting constitutive STAT3 signaling represents a promising molecular target for therapeutic approach. Using structure-based design, we develop...

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Detalles Bibliográficos
Autores principales:	Liu, Aiguo, Liu, Yan, Jin, Zhigang, Hu, Qun, Lin, Li, Jou, David, Yang, Jing, Xu, Zhenghu, Wang, Hong, Li, Chenglong, Lin, Jiayuh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463519/ https://www.ncbi.nlm.nih.gov/pubmed/23056374 http://dx.doi.org/10.1371/journal.pone.0046624

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