Heteromeric p97/p97(R155C) Complexes Induce Dominant Negative Changes in Wild-Type and Autophagy 9-Deficient Dictyostelium strains

Heterozygous mutations in the human VCP (p97) gene cause autosomal-dominant IBMPFD (inclusion body myopathy with early onset Paget’s disease of bone and frontotemporal dementia), ALS14 (amyotrophic lateral sclerosis with or without frontotemporal dementia) and HSP (hereditary spastic paraplegia). Mo...

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Detalles Bibliográficos
Autores principales: Arhzaouy, Khalid, Strucksberg, Karl-Heinz, Tung, Sze Man, Tangavelou, Karthikeyan, Stumpf, Maria, Faix, Jan, Schröder, Rolf, Clemen, Christoph S., Eichinger, Ludwig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463532/
https://www.ncbi.nlm.nih.gov/pubmed/23056506
http://dx.doi.org/10.1371/journal.pone.0046879

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