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Association of the Maternal MTHFR C677T Polymorphism with Susceptibility to Neural Tube Defects in Offsprings: Evidence from 25 Case-Control Studies

BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) is a critical enzyme in folate metabolism and is involved in DNA methylation, DNA synthesis, and DNA repair. In addition, it is a possible risk factor in neural tube defects (NTDs). The association of the C677T polymorphism in the MTHFR gene an...

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Detalles Bibliográficos
Autores principales:	Yan, Lifeng, Zhao, Lin, Long, Yan, Zou, Peng, Ji, Guixiang, Gu, Aihua, Zhao, Peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463537/ https://www.ncbi.nlm.nih.gov/pubmed/23056169 http://dx.doi.org/10.1371/journal.pone.0041689

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