Angiogenesis Impairment in Diabetes: Role of Methylglyoxal-Induced Receptor for Advanced Glycation Endproducts, Autophagy and Vascular Endothelial Growth Factor Receptor 2

Diabetes impairs physiological angiogenesis by molecular mechanisms that are not fully understood. Methylglyoxal (MGO), a metabolite of glycolysis, is increased in patients with diabetes. This study defined the role of MGO in angiogenesis impairment and tested the mechanism in diabetic animals. Endo...

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Detalles Bibliográficos
Autores principales: Liu, Hongtao, Yu, Shujie, Zhang, Hua, Xu, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463541/
https://www.ncbi.nlm.nih.gov/pubmed/23056421
http://dx.doi.org/10.1371/journal.pone.0046720

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463541/
https://www.ncbi.nlm.nih.gov/pubmed/23056421
http://dx.doi.org/10.1371/journal.pone.0046720

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