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α-bisabolol Is an Effective Proapoptotic Agent against BCR-ABL(+) Cells in Synergism with Imatinib and Nilotinib

We showed that α-bisabolol is active against primary acute leukemia cells, including BCR-ABL(+) acute lymphoblastic leukemias (ALL). Here we studied the activity of α-bisabolol against BCR-ABL(+) cells using 3 cell lines (K562, LAMA-84, CML-T1) and 10 primary BCR-ABL(+) ALL samples. We found that: (...

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Detalles Bibliográficos
Autores principales: Bonifacio, Massimiliano, Rigo, Antonella, Guardalben, Emanuele, Bergamini, Christian, Cavalieri, Elisabetta, Fato, Romana, Pizzolo, Giovanni, Suzuki, Hisanori, Vinante, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463553/
https://www.ncbi.nlm.nih.gov/pubmed/23056396
http://dx.doi.org/10.1371/journal.pone.0046674

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