Cargando…
Agrin and Synaptic Laminin Are Required to Maintain Adult Neuromuscular Junctions
As synapses form and mature the synaptic partners produce organizing molecules that regulate each other’s differentiation and ensure precise apposition of pre- and post-synaptic specializations. At the skeletal neuromuscular junction (NMJ), these molecules include agrin, a nerve-derived organizer of...
Autores principales: | Samuel, Melanie A., Valdez, Gregorio, Tapia, Juan C., Lichtman, Jeff W., Sanes, Joshua R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463559/ https://www.ncbi.nlm.nih.gov/pubmed/23056392 http://dx.doi.org/10.1371/journal.pone.0046663 |
Ejemplares similares
-
Shared Resistance to Aging and ALS in Neuromuscular Junctions of Specific Muscles
por: Valdez, Gregorio, et al.
Publicado: (2012) -
Laminins promote postsynaptic maturation by an autocrine mechanism at the neuromuscular junction
por: Nishimune, Hiroshi, et al.
Publicado: (2008) -
Agrin regulates CLASP2-mediated capture of microtubules at the neuromuscular junction synaptic membrane
por: Schmidt, Nadine, et al.
Publicado: (2012) -
The Role of Muscle microRNAs in Repairing the Neuromuscular Junction
por: Valdez, Gregorio, et al.
Publicado: (2014) -
A Novel Egr-1-Agrin Pathway and Potential Implications for Regulation of Synaptic Physiology and Homeostasis at the Neuromuscular Junction
por: MacDonald, Ryen, et al.
Publicado: (2017)