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The Primacy of β1 Integrin Activation in the Metastatic Cascade
After neoplastic cells leave the primary tumor and circulate, they may extravasate from the vasculature and colonize tissues to form metastases. β1 integrins play diverse roles in tumorigenesis and tumor progression, including extravasation. In blood cells, activation of β1 integrins can be regulate...
Autores principales: | Kato, Hisashi, Liao, Zhongji, Mitsios, John V., Wang, Huan-You, Deryugina, Elena I., Varner, Judith A., Quigley, James P., Shattil, Sanford J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463578/ https://www.ncbi.nlm.nih.gov/pubmed/23056350 http://dx.doi.org/10.1371/journal.pone.0046576 |
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