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The Primacy of β1 Integrin Activation in the Metastatic Cascade

After neoplastic cells leave the primary tumor and circulate, they may extravasate from the vasculature and colonize tissues to form metastases. β1 integrins play diverse roles in tumorigenesis and tumor progression, including extravasation. In blood cells, activation of β1 integrins can be regulate...

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Detalles Bibliográficos
Autores principales: Kato, Hisashi, Liao, Zhongji, Mitsios, John V., Wang, Huan-You, Deryugina, Elena I., Varner, Judith A., Quigley, James P., Shattil, Sanford J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463578/
https://www.ncbi.nlm.nih.gov/pubmed/23056350
http://dx.doi.org/10.1371/journal.pone.0046576

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